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Heart & Vascular Imaging: Beyond the ECG
Fishtown Medicine•9 min read
4.96 (124)

Heart & Vascular Imaging: Beyond the ECG

Ashvin Vijayakumar MD

Medically Reviewed

Ashvin Vijayakumar MD•Updated January 29, 2026
On This Page
  • What is the difference between the pump and the plumbing?
  • What are the common cardiac studies compared?
  • Why is coronary CTA with Cleerly the gold standard?
  • What do these scans cost in Philadelphia?
  • Is there a cheaper way to find out whether plaque has started?
  • Guidance from the clinic
  • What is the clinical sequence for cardiac imaging?
  • Red Flags: Seek Emergency Care
  • ✦Key Takeaways
  • Common Questions
  • What is the difference between a calcium score and a coronary CTA?
  • Do I need a calcium score if I am getting a CCTA?
  • How much radiation is in a coronary CTA?
  • Is a stress test or a CCTA better for chest pain?
  • What is an echocardiogram and when do I need one?
  • What is the role of cardiac MRI?
  • Will my insurance cover cardiac imaging?
  • How much does a coronary CTA cost without the Cleerly analysis?
  • Can an ultrasound find plaque instead of a CT scan?
  • How often should I repeat heart imaging?
  • Deep Questions
  • What is "soft plaque" and why is it so dangerous?
  • How does Cleerly AI change interpretation of CCTA scans?
  • What is the role of pericoronary fat attenuation in heart imaging?
  • How does an MRI evaluate myocarditis?
  • What is the difference between a stress echo and a nuclear stress test?
  • How does coronary calcium score regression compare to soft plaque regression?
  • What is FFR-CT and how is it different from Cleerly?
  • How does cardiac amyloidosis show up on imaging?
  • What is left atrial appendage closure imaging used for?
  • How does heart imaging change in younger patients with chest pain?
  • What is the role of carotid ultrasound in stroke prevention?
  • Why does Fishtown Medicine often pair cardiac imaging with advanced lipid panels?
  • Scientific References

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TL;DR30-second take

Heart imaging includes echocardiograms for the pump and valves, calcium scores for hardened plaque, coronary CTAs for soft and hard plaque, and cardiac MRI for tissue scarring. We use coronary CTA with Cleerly AI as the gold standard for measuring real plaque burden, since calcium scores miss the soft plaque that causes most heart attacks.

TL;DR: An EKG checks your heart's rhythm. It does not tell you whether your arteries are clogging up, and for that you need a picture. There are 4 options and they cost very different amounts, so knowing the ladder before you agree to anything matters. An ultrasound of the arteries in your neck and belly is the cheapest, usually covered, often under $100 cash for both, and it tells you whether plaque has started anywhere in your body. A calcium score is $100 to $150 and only sees old, hardened plaque. A CT scan of the heart arteries is about $400 to $450 and also sees the soft plaque, which is the kind that causes most heart attacks. That same CT scan with AI analysis added costs closer to $2,000. It is the same machine, the same trip, and the same radiation. What the extra money buys is a precise measurement you can compare against a scan years from now. If the question is simply whether you have plaque, you do not need the $2,000 version.

A standard ECG only tells us about your hearts electrical rhythm. To understand your risk of a heart attack, we need to see the plumbing and the pump. At Fishtown Medicine, we use advanced heart imaging, including coronary CT angiography (CCTA) with Cleerly AI, to find both calcified and soft plaque before it becomes a problem.

If you are over 40 with any cardiovascular risk factors, the question is no longer "should I get heart imaging," but "which scan answers my question." We help you decide.

How testing works here

Dr. Ash orders this the same way he orders everything else, as part of primary care, so it is not something you can buy from us by itself. A number with nobody to read it against the rest of your picture is how most people end up with a result sitting in a portal and no idea what to do next.

What that looks like from your side is straightforward. The lab or imaging center bills you directly, at their price, with nothing added by us. Dr. Ash sends the order, reads the result next to your history and your other labs, and turns it into a plan you leave with. If there is something specific you want measured, that is a good thing to say up front.

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What is the difference between the pump and the plumbing?

The difference between the pump and the plumbing is the system we are evaluating. We look at two distinct systems when we work up your heart.

  1. The pump (structure): We use echocardiograms (ultrasound) to see how well your heart valves work and how strong the heart muscle is pumping.
  2. The plumbing (arteries): We use CT scans (calcium scores or coronary CTAs) to see if there is any plaque buildup in the coronary arteries that could cause a heart attack.

Most patients need a look at both systems at some point, just not always at the same time.

What are the common cardiac studies compared?

Common cardiac studies compared:

StudyPrimary UseWhy it MattersNotes
Carotid and aortic ultrasoundA first look at whether plaque has started anywhere.Finds plaque in the 2 vessels sound sees well.No radiation; usually covered; often under $100 cash for both.
Coronary Calcium Score (CAC)Age 40-75 with intermediate risk.Quantifies hardened plaque only; misses soft plaque.No IV dye; low dose; self-pay around $100 to $150.
EchocardiogramMurmurs, shortness of breath, valve issues.Visualizes heart size and pumping strength.No radiation; no prep needed.
Nuclear Stress TestIntermediate risk with symptoms.Shows blood flow to the heart under stress.Uses IV tracer; moderate radiation.
Coronary CTA (standard read)Atypical chest pain or higher risk.Sees soft plaque as well as calcified.Uses IV dye; beta-blocker prep; self-pay around $400 to $450.
Coronary CTA with Cleerly AIWhen plaque needs to be measured and tracked over years.Reports every plaque by volume and type.Same scan, AI analysis added; self-pay closer to $2,000.
Cardiac MRICardiomyopathy or scarring.Best for tissue characterization.45-plus minutes; no radiation.

Why is coronary CTA with Cleerly the gold standard?

Coronary CTA with Cleerly is the gold standard for advanced cardiovascular imaging because it sees the plaque that causes heart attacks. Unlike a calcium score, which only sees old, calcified plaque, a CCTA can see the young, soft plaque most likely to rupture and cause a sudden heart attack.

This lets us be far more precise in our high cholesterol prevention strategy and in ApoB-targeted treatment. For patients with a family history of early heart disease or elevated Lp(a), the CCTA often changes the entire treatment plan.

A cardiac CT also captures the lungs it passes through, so a small lung nodule sometimes turns up on a scan ordered for the arteries. Our guide to the chest CT explains how those incidental findings are sized, sorted, and followed.

What do these scans cost in Philadelphia?

The distance between the cheapest and the most expensive option on that table is wider than most people expect, and knowing the ladder before you agree to anything matters, because the most expensive version is not always the one that answers your question.

A carotid and abdominal aortic ultrasound is at the bottom. Both are usually covered when there is a reason to order them, and paid in cash the 2 together often come in under $100 at a Philadelphia imaging center. A coronary calcium score runs about $100 to $150 cash and is rarely covered, since insurers still treat it as screening, though it is inexpensive enough that the coverage question seldom decides anything.

The step people are almost never told about is the coronary CT angiogram read the ordinary way, by a radiologist, which runs roughly $400 to $450 cash here. Adding the Cleerly AI analysis to that same scan brings it closer to $2,000, and some commercial plans will cover the underlying angiogram while declining the AI layer on top. That is the same trip to the same scanner and the same radiation dose in both cases. What the higher price buys is measurement: a plaque volume in cubic millimeters, broken out by type, that a scan 3 years from now can be compared against.

If the question in front of us is simply whether plaque exists and how urgently to treat it, the standard read answers it at a fifth of the cost. If we are going to spend years watching whether a plan is working, the measurement is worth paying for. These are cash prices at Philadelphia imaging centers rather than fixed rates, they move, and we confirm the current one and pass through any discount we have before you book anything.

Is there a cheaper way to find out whether plaque has started?

Yes, and it is one of the more useful things a preventive workup can borrow from ordinary radiology. Ultrasound is generally poor at finding plaque, because sound will not travel through bone or gas and most arteries sit too deep to see well. Two of them are the exception. The carotid arteries run close to the surface on either side of the neck, and the abdominal aorta is the largest vessel in the body, running from the heart down through the belly. Both are large enough and shallow enough that ultrasound sees them clearly.

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Scanning those 2 vessels answers a narrower question than a coronary CTA, and answering it is often enough to move a decision. Atherosclerosis is a whole-body process rather than a coronary one, so finding plaque in the neck or the aorta tells you the process has already begun somewhere, which turns a conversation about future risk into a conversation about disease you have today. For a 37-year-old weighing whether cholesterol can be handled through food and training alone, that distinction changes the answer.

What these scans cannot do is clear your coronary arteries. A normal carotid study does not mean the vessels feeding your heart are free of plaque, and anyone who tells you otherwise is overreading it. Ultrasound also takes longer than the CT does, because a person is holding the probe and has to work for every image, so plan on more chair time rather than less.

There are 2 more vessels to know about. A renal artery ultrasound looks at the arteries feeding the kidneys, and it is harder to get approved without documented high blood pressure, which is one of several reasons home blood pressure readings are worth taking before an appointment rather than after. An arterial ultrasound of the legs, often paired with an ankle-brachial index, looks for peripheral arterial disease and earns its place when there is leg pain with walking, a smoking history, or diabetes. Neither is a routine screen, and both are inexpensive when the indication is there.

Guidance from the clinic

Dr. Ash
"I start simple. For low-risk discomfort, we begin with an ECG and basic labs (ApoB, Lp(a)). But if your risk markers are elevated, we do not guess. We get a high-resolution map of your arteries. Finding plaque in your 40s is a gift. It gives us the chance to treat it before it ever becomes a crisis."

What is the clinical sequence for cardiac imaging?

The clinical sequence for cardiac imaging at Fishtown Medicine usually goes:

  1. Risk stratification: We start with an ECG, ApoB, Lp(a), and a thorough clinical history.
  2. Refine prevention: A coronary CTA gives us the full picture, calcified and soft plaque, to decide if you need a statin today. The same picture is what settles the harder question in the other direction, which is what happens when you stop a statin you have already been taking for years.
  3. Investigate symptoms: If you have exertional chest pain, we move to a stress test or coronary CTA.
  4. Tissue check: If we suspect heart failure, infiltrative disease, or structural issues, we order an echocardiogram or cardiac MRI.

Red Flags: Seek Emergency Care

Do not wait for an elective scan. Call 911 or go to the ER if you experience:

  1. Crushing chest pain: Pressure or tightness like an "elephant on the chest."
  2. Pain radiating: Discomfort that moves to the jaw, neck, or left arm.
  3. Sudden shortness of breath: Difficulty breathing even at rest.
  4. Syncope: Fainting or losing consciousness unexpectedly.
  5. Palpitations with lightheadedness: Irregular heartbeats with dizziness or fainting.
✦

Key Takeaways

  1. ECGs track rhythm; imaging tracks structure and plumbing.
  2. Calcium scores only detect old, calcified plaque, missing the soft, vulnerable plaque that causes most heart attacks.
  3. Coronary CTA is the gold standard for spotting dangerous soft plaque.
  4. A coronary CTA with a standard radiologist read costs roughly $400 to $450 cash in Philadelphia, while the same scan with Cleerly AI analysis runs closer to $2,000.
  5. Carotid and abdominal aortic ultrasound is the inexpensive first look at whether plaque has started, usually covered and often under $100 cash for both, though it cannot assess the coronary arteries.
  6. Chest pain should always be evaluated by a professional immediately.

A note on cost: any discount we negotiate on labs and imaging passes straight through to you, with no markup. Our affordable labs and imaging guide covers how the billing works.

Scientific References

  1. Gulati M, et al. "2021 AHA/ACC/ASE/CHEST/SAEM/SCCT/SCMR Guideline for the Evaluation and Diagnosis of Chest Pain." Journal of the American College of Cardiology. 2021.
  2. Williams MC, et al. "Coronary Atherosclerosis Imaging by Coronary CT Angiography." Circulation: Cardiovascular Imaging. 2020.
  3. Greenland P, et al. "Coronary Calcium Score and Cardiovascular Risk." Journal of the American College of Cardiology. 2018.
  4. Maron BA, et al. "Cardiac magnetic resonance imaging in cardiomyopathy." Journal of the American College of Cardiology. 2020.

Dr. Ash is a board-certified internal medicine physician at Fishtown Medicine in Philadelphia. He practices Medicine 3.0 preventive cardiology so your heart lasts as long as your ambition.

Ashvin Vijayakumar MD (Dr. Ash)

Fishtown Medicine | Diagnostics

2418 E York St, Philadelphia, PA 19125·(267) 360-7927·hello@fishtownmedicine.com·HSA/FSA Eligible

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Medical Disclaimer: This resource provides clinical context for educational purposes. In the world of Precision Medicine, there is no "one size fits all", the right plan must be matched to your unique lab work, physiology, and goals. Consult Dr. Ash to determine if this approach is right for you, particularly if you have chronic health conditions or are taking prescription medications.

Frequently Asked Questions

Common Questions

The difference between a calcium score and a coronary CTA is what each scan can see. A calcium score uses a non-contrast CT to measure only hardened, calcified plaque. A coronary CTA uses contrast and AI analysis (Cleerly) to see both calcified and soft plaque, giving a far more complete picture.
You do not need a separate calcium score if you are getting a CCTA. The CCTA captures all the calcium-score data plus the soft-plaque analysis. Some patients start with a calcium score for triage and only get a CCTA if the calcium is elevated or family history demands a closer look.
A coronary CTA delivers about 3 to 5 mSv of radiation, comparable to one year of background radiation, depending on the scanner and protocol. Modern dose-modulation techniques have reduced this substantially. We do not order CCTAs casually, but the dose is acceptable when the question is right.
A CCTA is generally better than a stress test for new chest pain in low-to-intermediate risk patients, based on the 2021 chest pain guidelines. A CCTA visualizes anatomy directly. A stress test only suggests there might be a blockage. Stress tests still have a role in known disease and post-stent monitoring.
An echocardiogram is an ultrasound of the heart that shows the chambers, valves, and pumping function. You need one if there is a heart murmur, unexplained shortness of breath, suspected heart failure, valve disease, or before certain medical procedures. It is fast, painless, and uses no radiation.
The role of cardiac MRI is tissue characterization. It can detect scarring (late gadolinium enhancement), inflammation (myocarditis), iron overload, and infiltrative diseases like amyloidosis. It is usually a second-line test ordered when an echocardiogram raises a specific question. It also keeps you inside the scanner for 45 minutes or more, so if you have ever had trouble staying still in an MRI, say so before the appointment is booked rather than on the table.
Insurance usually covers cardiac imaging when there is a clear clinical indication like symptoms, abnormal labs, or strong family history. Carotid and aortic ultrasounds are usually covered when there is a reason to order them. Calcium scores are typically self-pay at about $100 to $150. CCTAs and stress tests usually require prior authorization, which our team handles, and the Cleerly AI analysis is often declined even when the underlying scan is approved.
A coronary CT angiogram with a standard radiologist read runs roughly $400 to $450 self-pay at Philadelphia imaging centers, compared with closer to $2,000 for the same scan with Cleerly AI analysis added. It is the same appointment, the same scanner, and the same radiation dose. The higher price buys quantified plaque volumes that can be compared against a future scan, which matters when we plan to track treatment over years and matters much less when the question is simply whether plaque is present.
An ultrasound can find plaque in the carotid arteries of the neck and in the abdominal aorta, because both vessels are large and close enough to the surface for sound to image them well. Finding plaque there confirms that atherosclerosis has begun, which often changes how urgently we treat. It cannot assess the coronary arteries, so a normal carotid study does not rule out plaque in the arteries feeding the heart.
You should repeat heart imaging every 2 to 5 years if the first scan showed disease and we are tracking response to treatment. Stable patients with clear scans can wait 5 to 10 years. The right interval depends on your specific findings and risk profile.

Deep-Dive Questions

Soft plaque is a non-calcified, lipid-rich plaque with a thin fibrous cap. It is dangerous because it can rupture suddenly, exposing its contents to blood and triggering a clot that blocks the artery, causing a heart attack. Most heart attacks happen in soft plaques that did not narrow the artery enough to cause symptoms first.
Cleerly AI changes interpretation of CCTA scans by adding quantitative, reproducible measurement to what was once a subjective read. A radiologist might say "moderate plaque." Cleerly outputs a volume in cubic millimeters, broken down by plaque type. That precision lets us track regression and tailor treatment.
The role of pericoronary fat attenuation is detecting inflammation around the coronary arteries. Inflamed fat appears denser on CT, and elevated values predict future cardiac events. Some advanced CCTA protocols now include pericoronary fat analysis to flag high-risk patients with otherwise modest plaque.
An MRI evaluates myocarditis by showing patchy late gadolinium enhancement in a non-coronary distribution and elevated T2 signal indicating tissue swelling. This pattern is used to diagnose viral or post-vaccine myocarditis and to monitor recovery. It is more sensitive than echocardiography for early myocarditis.
The difference between a stress echo and a nuclear stress test is the imaging modality. A stress echo uses ultrasound to watch the heart contract before and after exercise. A nuclear stress test uses an IV tracer and gamma camera to image blood flow under stress. Stress echo uses no radiation. Nuclear stress test offers slightly higher sensitivity in some cases.
Coronary calcium score regression is rare. Soft plaque regression is achievable with intensive ApoB lowering, inflammation control, and lifestyle change. Calcium often increases over time even on statins, because dying soft plaque calcifies as it stabilizes. We watch soft plaque, not calcium, when assessing treatment response.
FFR-CT (HeartFlow) calculates the functional flow reserve across coronary stenoses from a CCTA dataset, telling us whether a blockage is limiting blood flow. Cleerly focuses on plaque burden and composition. The two are complementary: FFR-CT answers "is this blockage limiting flow?" Cleerly answers "what kind of plaque is here?"
Cardiac amyloidosis shows up on imaging as thickened heart walls on echocardiogram, a specific late gadolinium enhancement pattern on cardiac MRI, and characteristic uptake on technetium-pyrophosphate (PYP) nuclear scans. Recognition has surged because new therapies like tafamidis have made it a treatable cause of heart failure.
Left atrial appendage closure imaging, usually with transesophageal echo or cardiac CT, is used to plan and follow Watchman device placement in patients with atrial fibrillation who cannot take long-term anticoagulation. It maps the appendage anatomy accurately so the device fits.
Heart imaging changes in younger patients with chest pain because cardiovascular risk is lower and radiation cost is higher. We are more selective with CT, lean toward stress echo or cardiac MRI, and look harder for non-coronary causes like myocarditis, pericarditis, or musculoskeletal pain.
The role of carotid ultrasound in stroke prevention is screening the neck arteries for plaque and stenosis that could cause an ischemic stroke. It is often added to a cardiovascular workup in patients with high ApoB, family history of stroke, or unexplained dizziness. It uses no radiation.
Fishtown Medicine pairs cardiac imaging with advanced lipid panels (ApoB, Lp(a), oxidized LDL, hsCRP) because the imaging shows current disease and the labs show ongoing risk drivers. Imaging without labs answers "is there plaque?" Labs without imaging answer "are you on track?" Together they answer "what should we do next?"

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